In 2006, Louisburg College established its Campus Police Department to provide better protection and service to the campus and surrounding community. As campus safety is the number one priority for the college, campus police officers are on duty 24-hours a day, seven days a week. Officers' duties consist of patrolling the entire campus, securing buildings and property, issuing citations, making arrests for criminal violations, working special events and responding to calls for assistance. A part-time detective is also devoted to performing ongoing criminal investigations in order to make arrests or solve crimes that occur on campus. Certain felony investigations are handled exclusively by the Louisburg City Police Department.

The Campus Police office is located on the first floor of Davis Hall, room 100.